draft ยท Updated 2026-05-06
Contraindication / Caution Index
Public-safe index of caution themes to check before changing supplement or protocol use.
Use
This is a conservative review checklist, not medical advice. Use it to decide what needs more research, professional guidance, or careful testing before changing a stack.
Caution Themes
| Theme | Check For |
|---|---|
| Stimulating | Restlessness, irritability, anxiety, elevated tension, worse sleep |
| Sedating | Sluggishness, flat mood, sleepiness, reduced drive |
| Blood pressure | Lightheadedness, unusual pressure changes, stimulant/adaptogen overlap |
| Sleep risk | Late dosing, stimulating items, poor recovery |
| GI risk | Nausea, loose stool, constipation, reflux, gut discomfort |
| Bleeding risk | Medication context, surgery context, bruising changes |
| Medication caution | Any prescription or condition that could interact |
Avoid With
Document item-specific avoid-with notes on each Materia Medica page. Keep broad claims cautious and review them before making pages public.
Watch For
- Sleep disruption
- Mood flattening
- Overstimulation
- GI changes
- Blood pressure context
- New headaches or unusual symptoms
- Any effect strong enough to change normal daily function
Reduce Or Stop If
Reduce or stop and review if a new item is repeatedly associated with worse sleep, anxiety, gut upset, mood flattening, unusual physical symptoms, or a decline in daily function.